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Dengue NS1 Raw Material Pair

The dengue virus belongs to the genus Flavivirus of the Flaviviridae family and is mainly transmitted by Aedes aegypti. The dengue virus includes four serotypes (types I–IV) and the infection by any serotype of the dengue virus can cause a series of clinical symptoms, manifested as invisible infection, fever, dengue fever or more severe dengue hemorrhagic
fever and dengue shock syndrome.

NS1 is a non-structural glycoprotein of the dengue virus. Dengue virus NS1 protein can be detected in the serum of patients during the early stage of the dengue disease. The NS1 occurrence is earlier than the IgM antibody, hence the detection of NS1 antigen in the serum of acute-phase patients can be used for the early diagnosis of dengue virus infection.