Neurofilaments

Neurofilaments ELISA-VIDITEST Neurofilament-H (pNF-H) is intended to measure the concentration of phosphorylated forms of heavy neurofilaments in peripheral blood and cerebrospinal fluid. The ELISA uses sandwich of the mouse monoclonal antibody NF01 that binds to the phosphorylated epitopes on heavy neurofilaments and of mouse monoclonal antibody NF05 that reacts equaly with phosphorylated and non-phosphorylated forms of heavy neurofilaments. Phosphorylated heavy neurofilaments were detected in higher concentrations in diseases that involve central nervous system damage (Shaw et al. 2005). The kit except the human pNF-H detects porcine, bovine and rat pNF-H but not mouse pNF-H.