ELISA-VIDITEST anti-Rubella kits are intended for diagnosis of measles in children and adults including pregnant women and congenitally infected newborns. As a part of TORCH complex they are utilized for differential diagnosis of vertically transmissed infections from mother to fetus. They may be also used for differential diagnosis of exanthematous diseases and for monitoring of individual immune status. rubella
IgG anti-rubella antibodies have anamnestic character: appear in the first week of disease onset, reach a maximum level after few weeks and than persist in lower levels lifelong. IgM can be detected in early acute phase of the infection and disappear obviously after 3-5 months. In some patients, IgM anti-rubella antibodies persist for several months. Following vaccination seroconversion in anti-rubella IgG is significant, although the concentration of antibody is generally lower than in natural infection. Specific IgG can be detected up to 15 years, IgM on the average 8-12 weeks. A single antibody positivity does not provide proof of recent infection and cannot necessarily be equated with immune protection status. To obtain a final diagnosis, the patient history and clinical symptoms should be taken into consideration.