MicroArray - Affymetrix SNP
Analysis of both SNP and CNV made possible through 906K SNP probe and 946k CNV probbe equipped Affymetrix SNP Array.
Overview
More than 906,600 SNPs:
Unbiased selection of 482,000 SNPs; historical SNPs from the SNP Array 5.0
Selection of additional 424,000 SNPs
- Tag SNPs
- SNPs from chromosomes X and Y
- Mitochondrial SNPs
- New SNPs added to the dbSNP database
- SNPs in recombination hotspots
More than 946,000 copy number probes:
202,000 probes targeting 5,677 CNV regions from the Toronto Database of Genomic Variants
744,000 probes, evenly spaced along the genome
Detected 10 times more copy number changes than other SNP/CN platforms
Three times more coverage of CNPs; only platform with non-polymorphic probes
GTC 3.0 leverages new, high-resolution reference map and CNP calling algorithm developed by the Broad Institute