LactoGen is a RealTime PCR test allowing to identify the polymorphisms responsible for either lactase persistence or non-persistence, identifying the patient as lactose tolerant or intolerant.
It detects a single nucleotide transition that occurs upstream of the LCT gene, i.e. -13910 C>T.
The method allows to highlight three different genotypes:
• Genotype C/C -13910 entirely associated with lactose genetic intolerance (LNP)
• Genotype C/T -13910 T associated with a normal lactase activity (LP), having a lactose genetic tolerance
• Genotype T/T -13910 associated with lactase persistence also in adulthood (LP), having a lactose genetic tolerance